Cunningham A J, Turner J, Rosenbaum S, Rafferty T
Department of Anesthesiology, Yale University School of Medicine, New Haven, CT 06510.
Br J Anaesth. 1993 Jun;70(6):621-5. doi: 10.1093/bja/70.6.621.
We have measured cardiovascular changes associated with insufflation of carbon dioxide and the reverse Trendelenburg position during laparoscopic cholecystectomy, using transoesophageal echocardiography in 13 healthy patients. End-tidal carbon dioxide values increased after insufflation of carbon dioxide, with values significantly (P < 0.05) increased after lateral tilt positioning. Creation of a pneumoperitoneum was associated with increases (P < 0.05) in left ventricular end-systolic wall stress, concomitant with increases (P < 0.01) in peak airway pressure and systemic arterial pressure. In addition, left ventricular end-diastolic area decreased (P < 0.05) after reverse Trendelenburg positioning. Left ventricular ejection fraction was maintained throughout the study.
我们对13名健康患者在腹腔镜胆囊切除术期间,使用经食管超声心动图测量了与二氧化碳气腹和反特伦德伦伯格体位相关的心血管变化。二氧化碳气腹后呼气末二氧化碳值升高,侧卧位后该值显著升高(P < 0.05)。气腹的形成与左心室收缩末期壁应力增加(P < 0.05)相关,同时气道峰值压力和体动脉压力也增加(P < 0.01)。此外,反特伦德伦伯格体位后左心室舒张末期面积减小(P < 0.05)。在整个研究过程中左心室射血分数保持不变。