心力衰竭的治疗——接下来该怎么办？
The treatment of heart failure--what next?
作者信息
Davies R H, Sheridan D J
机构信息
Department of Academic Cardiology, St Mary's Hospital, London.
出版信息
Br J Clin Pharmacol. 1993 Jun;35(6):557-63. doi: 10.1111/j.1365-2125.1993.tb04181.x.
Abstract
- Despite demonstrable benefits in terms of symptomatic relief and improvement in prognosis, even the best treatments of heart failure currently available fall short of being ideal. We review the basis for newer approaches to the treatment of heart failure and discuss some of the agents which capitalize on current understanding of the underlying patho-physiology. 2. Several drugs, old and new, are presently being investigated by major clinical trials. We also consider some of the difficulties related to the design and conduct of such trials and suggest how drugs might be better assessed in the future.
摘要
- 尽管目前可用的心力衰竭最佳治疗方法在缓解症状和改善预后方面有明显益处，但仍未达到理想状态。我们回顾了心力衰竭治疗新方法的依据，并讨论了一些基于当前对潜在病理生理学理解的药物。2. 目前，几种新旧药物正在进行大型临床试验研究。我们还考虑了与此类试验设计和实施相关的一些困难，并提出了未来如何更好地评估药物的建议。
相似文献
1
The treatment of heart failure--what next?心力衰竭的治疗——接下来该怎么办？
Br J Clin Pharmacol. 1993 Jun;35(6):557-63. doi: 10.1111/j.1365-2125.1993.tb04181.x.
2
Heart failure and ACE inhibitors.心力衰竭与血管紧张素转换酶抑制剂
Practitioner. 1989 Mar 22;233(1465):436-42.
3
Diuretic usage in heart failure: a continuing conundrum in 2005.心力衰竭中利尿剂的使用：2005年仍未解决的难题。
Eur Heart J. 2005 Apr;26(7):644-9. doi: 10.1093/eurheartj/ehi176. Epub 2005 Feb 25.
4
Prevention of worsening heart failure: future focus.
Eur Heart J. 1998 Feb;19 Suppl B:B47-53.
5
Optimal treatment of heart failure in the elderly.老年人心力衰竭的最佳治疗方法。
Drugs Aging. 1997 Jun;10(6):435-43. doi: 10.2165/00002512-199710060-00004.
6
7
Beta-blockers in heart failure: potential of carvedilol.心力衰竭中的β受体阻滞剂：卡维地洛的潜力。
J Hum Hypertens. 1993 Feb;7 Suppl 1:S62-7.
8
9
Captopril in heart failure.卡托普利用于心力衰竭
Acta Physiol Hung. 1988;72 Suppl:79-83.
10
Epinephrine for acute decompensated heart failure and low output state: friend or foe?肾上腺素用于急性失代偿性心力衰竭和低心排血量状态：是友还是敌？
Int J Cardiol. 2011 Jun 16;149(3):384-5. doi: 10.1016/j.ijcard.2011.03.006. Epub 2011 Mar 24.
引用本文的文献
1
Acute and chronic effects of flosequinan on resting and exercise haemodynamics in congestive heart failure.氟司喹南对充血性心力衰竭患者静息和运动血流动力学的急性和慢性影响。
Br J Clin Pharmacol. 1993 Dec;36(6):539-46. doi: 10.1111/j.1365-2125.1993.tb00412.x.
本文引用的文献
1
Nifedipine and left ventricular function in beta-blocked patients.硝苯地平与β受体阻滞剂治疗患者的左心室功能
Br Heart J. 1981 Apr;45(4):457-9. doi: 10.1136/hrt.45.4.457.
2
Relationship of exercise capacity to resting left ventricular performance and basal plasma norepinephrine levels in patients with congestive heart failure.充血性心力衰竭患者运动能力与静息左心室功能及基础血浆去甲肾上腺素水平的关系
Am Heart J. 1982 Oct;104(4 Pt 1):725-31. doi: 10.1016/0002-8703(82)90003-5.
3
Relation of the renin-angiotensin-aldosterone system to clinical state in congestive heart failure.肾素-血管紧张素-醛固酮系统与充血性心力衰竭临床状态的关系
Circulation. 1981 Mar;63(3):645-51. doi: 10.1161/01.cir.63.3.645.
4
Acute haemodynamic effects of felodipine during beta blockade in patients with coronary artery disease.非洛地平在冠状动脉疾病患者β受体阻滞剂治疗期间的急性血流动力学效应
Br Heart J. 1984 Oct;52(4):431-4. doi: 10.1136/hrt.52.4.431.
5
Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure.血浆去甲肾上腺素作为慢性充血性心力衰竭患者预后的一项指标。
N Engl J Med. 1984 Sep 27;311(13):819-23. doi: 10.1056/NEJM198409273111303.
6
Minoxidil in patients with chronic left heart failure: contrasting hemodynamic and clinical effects in a controlled trial.慢性左心衰竭患者使用米诺地尔：一项对照试验中的血流动力学和临床效果对比
Circulation. 1984 Jul;70(1):63-8. doi: 10.1161/01.cir.70.1.63.
7
Increased plasma arginine vasopressin levels in patients with congestive heart failure.充血性心力衰竭患者血浆精氨酸加压素水平升高。
J Am Coll Cardiol. 1983 Jun;1(6):1385-90. doi: 10.1016/s0735-1097(83)80040-0.
8
Decreased catecholamine sensitivity and beta-adrenergic-receptor density in failing human hearts.衰竭的人类心脏中儿茶酚胺敏感性和β-肾上腺素能受体密度降低。
N Engl J Med. 1982 Jul 22;307(4):205-11. doi: 10.1056/NEJM198207223070401.
9
Renin relationships in congestive cardiac failure, treated and untreated.充血性心力衰竭（无论是否接受治疗）中的肾素关系
Am Heart J. 1970 Sep;80(3):329-42. doi: 10.1016/0002-8703(70)90098-0.
10
Abnormalities of the peripheral circulation and respiratory function in patients with severe heart failure.重度心力衰竭患者外周循环和呼吸功能异常。
Br Heart J. 1986 Jan;55(1):75-80. doi: 10.1136/hrt.55.1.75.
Zotero 插件