Ahmed F, Mohiduzzaman M, Jackson A A
Institute of Nutrition and Food Science, University of Dhaka, Bangladesh.
Br J Nutr. 1993 May;69(3):817-25. doi: 10.1079/bjn19930082.
The effect of Ascaris lumbricoides infection on retinol absorption was investigated in young children from a slum area of Dhaka City, Bangladesh. Twenty-four children aged 4-10 years were screened and in every case eggs of either Ascaris, Trichuris or hookworm were isolated from the stool. The average serum retinol was 0.91 (SD 0.35) mumol/l and sixteen children had levels below 1.05 mumol/l. This compared with a serum retinol concentration of 1.70 (SD 0.52) mumol/l in five reference children from a more privileged social background. An oral dose of retinol (41.8 mumol) was given to ten children in whom the concentration of Ascaris eggs in the stool varied. Less than 1% of the supplement could be recovered in the stools collected over the following 48 h. Ascaris worms were isolated from the stool and assayed for retinol content. In no case was retinol detected in the worms. These findings do not support the contention that infection with Ascaris predisposes to malabsorption of vitamin A.
在孟加拉国达卡市一个贫民窟地区的幼儿中，研究了蛔虫感染对视黄醇吸收的影响。对24名4至10岁的儿童进行了筛查，在每个病例中均从粪便中分离出蛔虫、鞭虫或钩虫的虫卵。血清视黄醇平均水平为0.91（标准差0.35）μmol/l，16名儿童的水平低于1.05μmol/l。相比之下，来自社会背景更优越的5名对照儿童的血清视黄醇浓度为1.70（标准差0.52）μmol/l。对10名粪便中蛔虫卵浓度不同的儿童口服一剂视黄醇（41.8μmol）。在接下来的48小时内收集的粪便中，不到1%的补充剂能够被回收。从粪便中分离出蛔虫并检测其视黄醇含量。在任何情况下，蛔虫中均未检测到视黄醇。这些发现不支持蛔虫感染易导致维生素A吸收不良的观点。
