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足癣外用十一烯酸:新视角

Topical undecylenic acid in tinea pedis: a new look.

作者信息

Smith E B, Powell R P, Graham J L, Ulrich J A

出版信息

Int J Dermatol. 1977 Jan-Feb;16(1):52-6. doi: 10.1111/j.1365-4362.1977.tb00741.x.

DOI:10.1111/j.1365-4362.1977.tb00741.x
PMID:832943
Abstract

One hundred and four patients with mycologically confirmed tinea pedis took part in a controlled clinical trial to determine the efficacy of undecylenic acid powder preparations in the treatment of their fungal infections. Clinical and mycological cures were obtained in 53% of those subjects treated with undecylenic acid powders as compared with 7% of those treated with the talc vehicle or left untreated. Undecylenic acid in a powder vehicle appears to be a safe and effective agent in the treatment of tinea pedis.

摘要

104例经真菌学确诊的足癣患者参与了一项对照临床试验,以确定十一烯酸散剂治疗真菌感染的疗效。使用十一烯酸散剂治疗的患者中,53%获得了临床和真菌学治愈,相比之下,使用滑石粉载体治疗或未治疗的患者中这一比例为7%。以散剂为载体的十一烯酸似乎是治疗足癣的一种安全有效的药物。

相似文献

1
Topical undecylenic acid in tinea pedis: a new look.足癣外用十一烯酸:新视角
Int J Dermatol. 1977 Jan-Feb;16(1):52-6. doi: 10.1111/j.1365-4362.1977.tb00741.x.
2
Comparison between undecylenic acid and tolnaftate in the treatment of tinea pedis.
Cutis. 1980 May;25(5):544-6, 549.
3
Comparison of over-the-counter agents for tinea pedis.足癣非处方用药的比较
Cutis. 1979 May;23(5):696-8.
4
Efficacy of undecylenic acid-zinc undecylenate powder in culture positive tinea pedis.十一烯酸-十一烯酸锌粉对培养阳性足癣的疗效
Int J Dermatol. 1980 Jan-Feb;19(1):51-4. doi: 10.1111/j.1365-4362.1980.tb01997.x.
5
[Tried and newly expanded local therapy of mycoses].[经实践检验且新拓展的真菌病局部治疗方法]
Mykosen. 1968 May 1;11(5):391-4.
6
ORAL AND TOPICAL TREATMENT OF TINEA PEDIS.足癣的口服及局部治疗
Clin Med (Northfield). 1963 Nov;70:2015-25.
7
[Experiences with tinea pedis in daily practice].[足癣在日常实践中的经验]
Arch Klin Exp Dermatol. 1966;227(1):564-8. doi: 10.1007/BF00502886.
8
Drugs for athlete's foot and tinea cruris.用于治疗足癣和股癣的药物。
Med Lett Drugs Ther. 1976 Nov 19;18(24):101-2.
9
Efinaconazole Topical Solution, 10% Efficacy in Patients with Onychomycosis and Coexisting Tinea Pedis.10% 艾氟康唑外用溶液治疗甲癣合并足癣患者的疗效
J Am Podiatr Med Assoc. 2015 Sep;105(5):407-11. doi: 10.7547/14-088.
10
A Phase 2, Controlled, Dose-Ranging Study of SB208, an Investigational Topical Nitric Oxide-Releasing Drug, for the Treatment of Tinea Pedis.一项关于SB208(一种正在研究的局部释放一氧化氮药物)治疗足癣的2期对照剂量范围研究。
J Drugs Dermatol. 2018 Aug 1;17(8):888-893.

引用本文的文献

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Topical treatments for fungal infections of the skin and nails of the foot.足部皮肤和指甲真菌感染的局部治疗方法。
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An overview of topical antifungal therapy in dermatomycoses. A North American perspective.皮肤真菌病的局部抗真菌治疗概述。北美视角。
Drugs. 1998 May;55(5):645-74. doi: 10.2165/00003495-199855050-00004.