Tschen E H, Becker L E, Ulrich J A, Hoge W H, Smith E B
Cutis. 1979 May;23(5):696-8.
To evaluate the relative effectiveness of the treatment of tinea pedis, we performed a double-blind study comparing undecylenic acid ointment, tolnaftate cream, and a placebo. Ninety patients with clinically and mycologically proven tinea pedis took part in this clinical trial. Our results showed both agents to be superior to the placebo, but there was no significant difference in effectiveness between the two active agents. We observed no side effects with the preparations used.
为评估足癣治疗的相对有效性,我们进行了一项双盲研究,比较十一烯酸软膏、托萘酯乳膏和一种安慰剂。90例临床及真菌学确诊的足癣患者参与了该临床试验。我们的结果显示,两种药物均优于安慰剂,但两种活性药物在有效性方面无显著差异。我们观察到所使用的制剂无副作用。