Ruiz-Gutiérrez V, Vazquez C M
Instituto de la Grasa y sus Derivados, (C.S.I.C.), Sevilla, Spain.
Exp Toxicol Pathol. 1993 May;45(2-3):183-8. doi: 10.1016/S0940-2993(11)80503-8.
The lipid composition and the fatty acid profile of the lipid fraction (phospholipid, triacylglycerol, diacylglycerol and cholesterol ester) of the caecum were studies 6 weeks after both 50% and 75% distal small bowel resection (DSBR). Triacylglycerol (TG) and cholesterol ester (CE) levels were decreased after resection but the total phospholipid (PL), free cholesterol (FC), and diacylglycerol (DG) contents were not significantly modified after the operation. Different fatty acid changes in the caecum lipid fractions were found after the surgical operation, with the greatest differences after 75% DSBR. Saturated fatty acids were increased in PL, TG and CE fractions as a consequence of DSBR. Similarly, these fractions presented the lowest amounts of n-6 and polyunsaturated fatty acids after resection. On the contrary, the levels of saturated fatty acids was decreased and both n-6 and polyunsaturated fatty acid levels increased in the DG fraction of resected animals. These results are discussed in terms of adaptation to intestinal resection.
在进行50%和75%远端小肠切除（DSBR）6周后，对盲肠脂质部分（磷脂、三酰甘油、二酰甘油和胆固醇酯）的脂质组成和脂肪酸谱进行了研究。切除后三酰甘油（TG）和胆固醇酯（CE）水平降低，但总磷脂（PL）、游离胆固醇（FC）和二酰甘油（DG）含量在术后无显著变化。手术后在盲肠脂质部分发现了不同的脂肪酸变化，75% DSBR后差异最大。由于DSBR，PL、TG和CE部分的饱和脂肪酸增加。同样，这些部分在切除后n-6和多不饱和脂肪酸含量最低。相反，切除动物的DG部分中饱和脂肪酸水平降低，n-6和多不饱和脂肪酸水平均升高。从对肠道切除的适应性方面对这些结果进行了讨论。
