Liu F S
Cancer Institute, Chinese Academy of Medical Sciences, Beijing.
Zhonghua Bing Li Xue Za Zhi. 1993 Feb;22(1):36-7.
According to the standard histological grading (formation of glandular structures, differentiation and mitosis of the cancer cells), totally 826 cases of breast cancer were graded into three groups, including: grade I: 291 cases, 35.2%, grade II: 412 cases, 49.9%, and grade III: 123 cases, 14.9%. The 5-year and 10-year survival rates were as follows: grade I: 78.4%(228/291) and 56.5%(148/262); grade II: 51.2%(211/412) and 35.2%(125/355); and grade III: 44.7%(55/123) and 29.0%(31/107) respectively. Among 599 breast cancer cases, there were 293 accompanied with lymph nodes positive to cancer cells (48.9%). The relationships between patients with lymph nodes positive to cancer cells and the histological grading were: grade I 41.4%(92/222); grade II 48.8%(137/281) and grade III 66.7%(64/96) and all were significant statistically. In this studied group, cancer cell emboli were found in 287 cases (34.7%) including: grade I 20.6%; grade II 41.5% and grade III 45.6%. Those cancers with high cell differentiation gave a low incidence of cancer cell embolus.
根据标准组织学分级（腺结构形成、癌细胞分化和有丝分裂），共826例乳腺癌患者被分为三组，包括：I级：291例，占35.2%；II级：412例，占49.9%；III级：123例，占14.9%。5年和10年生存率如下：I级：78.4%（228/291）和56.5%（148/262）；II级：51.2%（211/412）和35.2%（125/355）；III级：分别为44.7%（55/123）和29.0%（31/107）。在599例乳腺癌病例中，有293例伴有癌细胞阳性淋巴结（48.9%）。癌细胞阳性淋巴结患者与组织学分级的关系为：I级41.4%（92/222）；II级48.8%（137/281），III级66.7%（64/96），差异均有统计学意义。在该研究组中，发现287例（34.7%）有癌细胞栓子，包括：I级20.6%；II级41.5%，III级45.6%。癌细胞分化程度高的癌症，癌细胞栓子的发生率较低。
