DePaolis A M, Schnabel G, Katz S E, Rosen J D
J Assoc Off Anal Chem. 1977 Jan;60(1):210-2.
A rapid and sensitive high pressure liquid chromatographic method for the analysis of dexamethasone (9 alpha - fluoro - 11 beta, 17 alpha, 21 - trihydroxy - 16 alpha - methylpregna - 1,4-diene-3,20-dione) in milk has been developed. The corticosteroid can be quantitated at 20 ppb, with the limit of detectability estimated at 5 ppb. Recoveries ranged from 72 to 94%. After dexamethasone was injected into 5 Holstein-Friesian cows, no residues were dound in milk, even after the first milking.
已开发出一种快速灵敏的高压液相色谱法，用于分析牛奶中的地塞米松（9α-氟-11β，17α，21-三羟基-16α-甲基孕甾-1,4-二烯-3,20-二酮）。该皮质类固醇的定量限为20 ppb，检测限估计为5 ppb。回收率在72%至94%之间。将地塞米松注射到5头荷斯坦-弗里生奶牛体内后，即使在首次挤奶后，牛奶中也未检测到残留。
