Pierro L, Brancato R, Zaganelli E
Department of Ophthalmology, University of Milano, Italy.
Acta Ophthalmol (Copenh). 1993 Apr;71(2):169-72. doi: 10.1111/j.1755-3768.1993.tb04984.x.
The aim of this study was to prove the existence of a correlation between corneal thickness and glycaemic control in insulin-dependent patients. Ultrasound pachometry and blood glucose measurements were taken in 87 patients three times a day: fasting, two, and four hours after lunch. The sample was divided into three groups of patients: 30 of them did not have retinopathy, 30 presented background retinopathy and 27 proliferative retinopathy. Thirty normal age-matched subjects were the control group. No correlation was found between pachometry values, blood glucose and duration of diabetes in the three groups (p > 0.05). A significant increase in corneal thickness was found in patients with background and proliferative retinopathy compared to the others (p < 0.01). No corneal thickness differences resulted between background and proliferative retinopathy (p = 0.74).
本研究的目的是证明胰岛素依赖型患者的角膜厚度与血糖控制之间存在相关性。对87例患者每天进行三次超声角膜测厚和血糖测量：空腹、午餐后两小时和四小时。样本分为三组患者：其中30例没有视网膜病变，30例有背景性视网膜病变，27例有增殖性视网膜病变。30名年龄匹配的正常受试者作为对照组。三组的角膜测厚值、血糖和糖尿病病程之间均未发现相关性（p>0.05）。与其他患者相比，有背景性和增殖性视网膜病变的患者角膜厚度显著增加（p<0.01）。背景性视网膜病变和增殖性视网膜病变之间的角膜厚度没有差异（p=0.74）。
