Janiec S, Rzendkowski M, Bolek S
Ophthalmological Clinic of Silesian Medical Academy, Katowice, Poland.
Int Ophthalmol. 1994;18(4):205-9. doi: 10.1007/BF00951798.
We measured the corneal autofluorescence in groups with different levels of diabetic retinopathy severity (72 eyes of 46 patients) and in age-matched non-diabetic controls (34 eyes of 24 controls). We also estimated the corneal endothelium cell count and pachymetry with a contact specular microscope. For the controls, mean corneal autofluorescence was 8.8 ng equivalents fluorescein/ml (SD 0.3). Results showed increased autofluorescence of the cornea in diabetic patients (mean 17.9 ng equivalents fluorescein/ml, SD 4.2), related to the duration of diabetes (P < 0.05) and to the severity of diabetic retinopathy (P < 0.0001). Corneal endothelial cell count results showed no statistically significant relation to corneal autofluorescence (P < 0.6), indicating that the increased autofluorescence cannot be attributed to a change in corneal cell density.
我们测量了不同严重程度糖尿病视网膜病变患者组（46例患者的72只眼）以及年龄匹配的非糖尿病对照组（24例对照的34只眼）的角膜自发荧光。我们还使用接触式镜面显微镜估计角膜内皮细胞计数和角膜厚度。对于对照组，平均角膜自发荧光为8.8纳克当量荧光素/毫升（标准差0.3）。结果显示糖尿病患者角膜自发荧光增加（平均17.9纳克当量荧光素/毫升，标准差4.2），这与糖尿病病程（P < 0.05）和糖尿病视网膜病变严重程度（P < 0.0001）相关。角膜内皮细胞计数结果显示与角膜自发荧光无统计学显著关系（P < 0.6），表明自发荧光增加不能归因于角膜细胞密度的变化。
