Skov T, Weiner J, Pukkala E, Malker H, Andersen A, Lynge E
Danish Cancer Registry, Copenhagen.
Arch Environ Health. 1993 May-Jun;48(3):176-80. doi: 10.1080/00039896.1993.9940817.
In an effort to evaluate a hypothesis raised by findings in Denmark that painters might experience an increased risk for pharyngeal and oral cancer, data were collected about these cancers among painters in Norway, Sweden, and Finland. The possible confounding effects of alcohol and tobacco were gauged by collecting data about cancer of the lung, larynx, esophagus, liver, and bladder, and about mortality from liver cirrhosis. Consistently increased risks for lung cancer among painters were found. The risks for cancer of the oral cavity and/or pharynx were increased in Norway, Sweden, and Finland, but not to the same extent as was observed in Denmark. The risks for cancer of the esophagus were slightly increased as were the risks for cancer of the liver and for cirrhosis of the liver in Denmark and Finland. The data from Norway, Sweden, and Finland could thus neither substantiate nor disprove the hypothesis that painters may experience an increased risk for cancer of the pharynx and oral cavity as a result of occupational exposures.
为了评估丹麦研究结果所提出的一个假设，即画家可能患咽癌和口腔癌的风险增加，收集了挪威、瑞典和芬兰画家患这些癌症的数据。通过收集肺癌、喉癌、食管癌、肝癌和膀胱癌的数据以及肝硬化死亡率的数据，来衡量酒精和烟草可能产生的混杂效应。结果发现，画家患肺癌的风险持续增加。挪威、瑞典和芬兰画家患口腔和/或咽癌的风险增加了，但增加程度不如在丹麦观察到的那样。丹麦和芬兰画家患食管癌的风险略有增加，患肝癌和肝硬化的风险也有所增加。因此，挪威、瑞典和芬兰的数据既不能证实也不能反驳画家可能因职业暴露而患咽癌和口腔癌风险增加这一假设。
