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Isolation and characterization of a novel type of glycosphingolipid from Neanthes diversicolor.

作者信息

Noda N, Tanaka R, Miyahara K, Kawasaki T

机构信息

Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Japan.

出版信息

Biochim Biophys Acta. 1993 Jul 21;1169(1):30-8.

PMID:8334147
Abstract

Five glycosphingolipids were obtained in the pure state from the marine annelid, Neanthes diversicolor. Final isolation of the individual compound was achieved by means of preparative HPLC with a reversed phase column in a recycling mode. They were assigned the structures, 1-O-beta-D-(6-O-[2'-(trimethylammonio)- ethylphosphoryl])galactopyranosyl, -N-hexadecanoyl-(4E,8E)-sphingadiene (1), -N-hexadecanoyl-(4E)-sphingenine (2), -N-heptadecanoyl-(4E)-sphingenine (3), -N-octadecanoyl-(4E)-sphingenine (4) and -N-hexadecanoyl-sphinganine (5). It is noted that they are the monogalactosyl ceramides carrying the phosphocholine group in the galactose moiety, and that one of them contains an odd numbered fatty acid residue.

摘要

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