Hosmane B, Maurath C, McConnell M
Department 436, Abbott Laboratories, Abbott Park, IL 60064.
Comput Methods Programs Biomed. 1993 Apr;39(3-4):285-8. doi: 10.1016/0169-2607(93)90030-o.
The urinary flow rates of normal individuals depend on the initial bladder volume in a non-linear fashion (J. Urol. 109 (1973) 874). A flow rate nomogram was developed by Siroky, Olsson and Krane, (J. Vol. 122 (1979) 665), taking the non-linear relationship into account, as an aid in the interpretation of urinary flow rate data. The use of a flow rate nomogram is to differentiate normal from obstructed individuals and is useful in the post operative follow-up of urinary outflow obstruction. It has been shown (J. Urol. 123 (1980) 123) that the flow rate nomogram is an objective measure of the efficacy of medical or surgical therapy. Instead of manually reading nomogram values from the flow rate nomogram, an algorithm is developed using polynomial regression to fit the flow rate nomograms and hence compute nomogram values directly from the fitted nomogram equations.
正常个体的尿流率以非线性方式取决于初始膀胱容量（《泌尿学杂志》第109卷，1973年，第874页）。西罗基、奥尔松和克兰（《泌尿学杂志》第122卷，1979年，第665页）考虑到这种非线性关系，绘制了一张尿流率列线图，以辅助解释尿流率数据。尿流率列线图的用途是区分正常个体和梗阻个体，在尿流梗阻术后随访中很有用。研究表明（《泌尿学杂志》第123卷，1980年，第123页），尿流率列线图是评估药物或手术治疗效果的客观指标。不再从尿流率列线图上手动读取列线图值，而是开发了一种算法，使用多项式回归来拟合尿流率列线图，从而直接从拟合的列线图方程计算列线图值。
