Voloshenovich M I, Labusheva M A, Ugolev A M, Pishak V P
Fiziol Zh (1978). 1993 Jan-Feb;39(1):107-12.
Under conditions of chronic experiment the circadian cycle of glucose transport was determined. An isolated proximal area of the small intestine was perfused by glucose, fructose, medical bile and Ringer's solutions in various intervals of the 24 hour period. The circadian cycle of glucose absorption is disturbed in the fasting rats. Various substrates differently alter their amplitude and acro-phase of absorption. Ringer's solution perfusion shifts the acro-phase absorption to evening time, while that of fructose occurs during day time and that of bile takes place at night. The circadian cycle of the fed rats is less subject to shifts. Fasting is a powerful exogenous factor causing structural changes in the small intestine and altering the circadian cycle of glucose absorption.
在慢性实验条件下，测定了葡萄糖转运的昼夜节律周期。在24小时周期的不同时间段，用葡萄糖、果糖、医用胆汁和林格氏液灌注小肠的孤立近端区域。禁食大鼠的葡萄糖吸收昼夜节律周期受到干扰。各种底物对其吸收的幅度和尖峰相位有不同的影响。林格氏液灌注使尖峰相位吸收转移到傍晚时间，而果糖的尖峰相位吸收发生在白天，胆汁的则在夜间。进食大鼠的昼夜节律周期较不易发生变化。禁食是导致小肠结构改变并改变葡萄糖吸收昼夜节律周期的一个强大外源性因素。
