Yeung W S, Chen H, Chan S T
Department of Zoology, University of Hong Kong.
Gen Comp Endocrinol. 1993 Mar;89(3):313-22. doi: 10.1006/gcen.1993.1039.
The seasonal gonadal steroidogenesis of Monopterus albus in relation to natural sex reversal was studied by in vitro time-course incubations. In vitro steroid metabolisms varied with the developmental stages of the gonad. In the female stage, the major products were either 3 beta-hydroxy-5 alpha-androstan-17-one or unidentified metabolites, depending on the season. In the males, 11-oxotestosterone was the major product during the prespawning, reproductively active period, while in other periods of the seasonal cycle, 5 alpha-reduced metabolites were more abundant. In the intersexes, the steroidogenic pattern changed from a female to a male pattern, i.e., the production of 11-oxotestosterone increased and that of the unidentified metabolites decreased.
通过体外时间进程培养研究了黄鳝季节性性腺类固醇生成与自然性逆转的关系。体外类固醇代谢随性腺发育阶段而变化。在雌性阶段，主要产物要么是3β-羟基-5α-雄甾烷-17-酮，要么是未鉴定的代谢产物，这取决于季节。在雄性中，11-氧睾酮是产卵前生殖活跃期的主要产物，而在季节性周期的其他时期，5α-还原代谢产物更为丰富。在雌雄同体中，类固醇生成模式从雌性模式转变为雄性模式，即11-氧睾酮的产量增加，未鉴定代谢产物的产量减少。
