Yamazaki T, Sakurai N, Honda A, Nakada H, Yoshizawa H, Hashizume S
Department of Pediatrics, Saitama Medical School.
Kansenshogaku Zasshi. 1993 Jun;67(6):589-93. doi: 10.11150/kansenshogakuzasshi1970.67.589.
Chlamydia pneumoniae (C. pneumoniae) was isolated from respiratory tract of 4 girls. Case 1 is 5-year-old, diagnosed as pneumonia, had had a prolonged productive cough. She was treated with RKM with improvement of symptoms, however, C. pneumoniae was isolated repeatedly and was not deleted. Neither anti-mycoplasmal nor viral antibodies were positive and no significant pathogens were cultured from nasophrayngeal swabs. Case 2, the sister of case 1, is a 3-year-old girl with acute bronchitis treated with EM. C. pneumoniae was negative on the tenth day after treatment. Case 3, a 5-year-old girl, had a fever and was diagnosed as bronchopneumonia with a mild attack of bronchial asthma. She was initially treated with CFIX followed by therapy including EM. Her symptoms had disappeared after treatment and anti-mycoplasmal antibody was 1:320. Case 4 was an asymptomatic carrier of C. pneumoniae. Specimen was obtained at regular health examinations of junior high school. C. pneumoniae was isolated from a 14-year-old girl without respiratory symptoms. Clinical figures of C. pneumoniae infections varies from asymptomatic carrier to pneumonia. Pathogens other than C. pneumoniae could modify symptoms of infections. Precise examinations of these cases would establish a proper management of a C. pneumoniae infection.
从4名女孩的呼吸道中分离出肺炎衣原体。病例1为5岁，诊断为肺炎，有长期的咳痰咳嗽症状。她接受了强力霉素治疗，症状有所改善，但肺炎衣原体被反复分离出来且未被清除。抗支原体和病毒抗体均为阴性，鼻咽拭子未培养出重要病原体。病例2是病例1的妹妹，为一名3岁患急性支气管炎的女孩，接受了红霉素治疗。治疗后第10天肺炎衣原体呈阴性。病例3是一名5岁女孩，发热，被诊断为支气管肺炎并伴有轻度支气管哮喘发作。她最初接受头孢克肟治疗，随后接受包括红霉素在内的治疗。治疗后她的症状消失，抗支原体抗体为1:320。病例4是肺炎衣原体的无症状携带者。样本是在初中学生定期健康检查时采集的。从一名无呼吸道症状的14岁女孩身上分离出肺炎衣原体。肺炎衣原体感染的临床表现从无症状携带者到肺炎各不相同。除肺炎衣原体之外的病原体可能会改变感染症状。对这些病例进行精确检查将有助于对肺炎衣原体感染进行适当管理。
