氨基酸与肽。十八。与纤维蛋白α链N端部分相关的合成肽及其对纤维蛋白原/凝血酶凝血的抑制作用。
Amino acids and peptides. XVIII. Synthetic peptides related to N-terminal portion of fibrin alpha-chain and their inhibitory effect on fibrinogen/thrombin clotting.
作者信息
Kawasaki K, Miyano M, Hirase K, Iwamoto M
机构信息
Faculty of Pharmaceutical Sciences, Kobe-Gakuin University, Japan.
出版信息
Chem Pharm Bull (Tokyo). 1993 May;41(5):975-7. doi: 10.1248/cpb.41.975.
PMID:8339344
Abstract
Peptide analogs of the N-terminal portion of fibrin alpha-chain were prepared and their inhibitory effects on fibrinogen/thrombin clotting were examined. Of the synthetic peptides, H-Gly-Pro-Arg-Pro-Pro-NH2 exhibited the most potent inhibitory effect.
摘要
制备了纤维蛋白α链N端部分的肽类似物，并检测了它们对纤维蛋白原/凝血酶凝血的抑制作用。在合成肽中，H-Gly-Pro-Arg-Pro-Pro-NH2表现出最强的抑制作用。
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