鉴定出异戊烯基胍类化合物鹰嘴豆芽素A为糙果赤箭莎（毒莎草）的毒性成分。
Identification of galegine, an isoprenyl guanidine, as the toxic principle of Schoenus asperocarpus (poison sedge).
作者信息
Huxtable C R, Dorling P R, Colegate S M
机构信息
School of Veterinary Studies, Murdoch University, Western Australia.
出版信息
Aust Vet J. 1993 May;70(5):169-71. doi: 10.1111/j.1751-0813.1993.tb06120.x.
Abstract
An isoprenyl guanidine, galegine, was isolated from the Western Australian sedge Schoenus asperocarpus (Cyperaceae). Synthetic galegine was shown to reproduce the clinical and pathological features of poisoning by this plant. Preliminary results suggest that the massive thoracic effusion observed in sedge poisoning is the result of a direct effect on pulmonary vascular permeability.
摘要
从西澳大利亚莎草科植物糙果赤箭莎（Schoenus asperocarpus）中分离出一种异戊烯基胍——山羊豆碱。合成的山羊豆碱被证明能重现该植物中毒的临床和病理特征。初步结果表明，在莎草中毒中观察到的大量胸腔积液是对肺血管通透性产生直接影响的结果。
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