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Crotoxin, the neurotoxin of South American rattlesnake venom, is a presynaptic toxin acting like beta-bungarotoxin.

作者信息

Chang C C, Lee J D

出版信息

Naunyn Schmiedebergs Arch Pharmacol. 1977 Jan;296(2):159-68. doi: 10.1007/BF00508469.

DOI:10.1007/BF00508469
PMID:834316
Abstract
摘要

相似文献

1
Crotoxin, the neurotoxin of South American rattlesnake venom, is a presynaptic toxin acting like beta-bungarotoxin.
Naunyn Schmiedebergs Arch Pharmacol. 1977 Jan;296(2):159-68. doi: 10.1007/BF00508469.
2
Short communications the presynaptic neuromuscular blocking action of taipoxin. A comparison with beta-bungarotoxin and crotoxin.
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3
Presynaptic actions of Mojave toxin isolated from Mojave rattlesnake (crotalus scutulatus) venom.从莫哈韦响尾蛇（角响尾蛇）毒液中分离出的莫哈韦毒素的突触前作用。
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4
Effects of Sr2+ and Mg2+ on the phospholipase A and the presynaptic neuromuscular blocking actions of beta-bungarotoxin, crotoxin and taipoxin.Sr2+和Mg2+对磷脂酶A以及β-银环蛇毒素、响尾蛇毒素和太攀蛇毒素的突触前神经肌肉阻断作用的影响。
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The modes of action of whole Dendroaspis jamesoni venom of skeletal nerve-muscle preparations.詹氏树眼镜蛇全毒液对骨骼肌神经-肌肉标本的作用方式。
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6
The presynaptic neuromuscular blocking effect and phospholipase A2 activity of textilotoxin, a potent toxin isolated from the venom of the Australian brown snake, Pseudonaja textilis.
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7
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[A comparison of the neuromuscular action of crotamine and the venom of Crotalus durissus terrificus var. crotaminicus. 2. Isolated preparations].[响尾蛇胺与杜氏眼镜蛇变种克罗塔米尼库斯毒液的神经肌肉作用比较。2. 离体标本]
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Suramin inhibits the toxic effects of presynaptic neurotoxins at the mouse motor nerve terminals.苏拉明可抑制突触前神经毒素对小鼠运动神经末梢的毒性作用。
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Biological and Medical Aspects Related to South American Rattlesnake (Linnaeus, 1758): A View from Colombia.与南美响尾蛇（Linnaeus，1758）相关的生物学和医学方面：来自哥伦比亚的观点。
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本文引用的文献

1
Observations on the isolated phrenic nerve diaphragm preparation of the rat.关于大鼠膈神经膈肌分离标本的观察
Br J Pharmacol Chemother. 1946 Mar;1(1):38-61. doi: 10.1111/j.1476-5381.1946.tb00025.x.
2
A simplified method of evaluating dose-effect experiments.一种评估剂量效应实验的简化方法。
J Pharmacol Exp Ther. 1949 Jun;96(2):99-113.
3
ISOLATION OF NEUROTOXINS FROM THE VENOM OF BUNGARUS MULTICINCTUS AND THEIR MODES OF NEUROMUSCULAR BLOCKING ACTION.从银环蛇毒液中分离神经毒素及其神经肌肉阻断作用方式
自毁的食欲：在非洲-亚洲眼镜蛇属蛇毒中探测猎物选择性结合的 α-神经毒素。
Toxins (Basel). 2020 Mar 23;12(3):205. doi: 10.3390/toxins12030205.
4
Immunotherapeutic potential of Crotoxin: anti-inflammatory and immunosuppressive properties.响尾蛇毒素的免疫治疗潜力：抗炎和免疫抑制特性。
J Venom Anim Toxins Incl Trop Dis. 2018 Dec 17;24:39. doi: 10.1186/s40409-018-0178-3. eCollection 2018.
5
Secreted Phospholipases A₂ from Animal Venoms in Pain and Analgesia.动物毒液中的分泌型磷脂酶 A₂与疼痛和镇痛。
Toxins (Basel). 2017 Dec 19;9(12):406. doi: 10.3390/toxins9120406.
6
Pancreatic and snake venom presynaptically active phospholipases A2 inhibit nicotinic acetylcholine receptors.胰腺和蛇毒突触前活性磷脂酶A2抑制烟碱型乙酰胆碱受体。
PLoS One. 2017 Oct 12;12(10):e0186206. doi: 10.1371/journal.pone.0186206. eCollection 2017.
7
Biophysical studies suggest a new structural arrangement of crotoxin and provide insights into its toxic mechanism.生物物理研究提示了一个 crotoxin 的新结构排列，并为其毒性机制提供了新的见解。
Sci Rep. 2017 Mar 3;7:43885. doi: 10.1038/srep43885.
8
In vitro antiophidian mechanisms of Hypericum brasiliense choisy standardized extract: quercetin-dependent neuroprotection.巴西金丝桃标准化提取物的体外抗蛇毒机制：槲皮素依赖性神经保护作用。
Biomed Res Int. 2013;2013:943520. doi: 10.1155/2013/943520. Epub 2013 Dec 31.
9
In vitro antiophidian properties of Dipteryx alata Vogel bark extracts.巴西苏木树皮提取物的体外抗蛇毒特性。
Molecules. 2010 Aug 30;15(9):5956-70. doi: 10.3390/molecules15095956.
10
Induction of giant miniature end-plate potentials during blockade of neuromuscular transmission by textilotoxin.在筒箭毒碱阻断神经肌肉传递期间巨型微小终板电位的诱发
Naunyn Schmiedebergs Arch Pharmacol. 1995 Jul;352(1):79-87. doi: 10.1007/BF00169193.
Arch Int Pharmacodyn Ther. 1963 Jul 1;144:241-57.
4
The isolated chick biventer cervicis nerve-muscle preparation.离体鸡颈二腹肌神经-肌肉标本。
Br J Pharmacol Chemother. 1960 Sep;15(3):410-1. doi: 10.1111/j.1476-5381.1960.tb01264.x.
5
Quantal components of the end-plate potential.终板电位的量子成分。
J Physiol. 1954 Jun 28;124(3):560-73. doi: 10.1113/jphysiol.1954.sp005129.
6
The effects of taipoxin and notexin on the function and fine structure of the murine neuromuscular junction.太攀蛇毒素和诺氏蛇毒素对小鼠神经肌肉接头功能及精细结构的影响。
Neuroscience. 1976 Jun;1(3):175-80. doi: 10.1016/0306-4522(76)90074-9.
7
Pharmacology of crystalline crotoxin. II. Neuromuscular blocking action.结晶巴豆油毒素的药理学。II. 神经肌肉阻断作用。
Mem Inst Butantan. 1966;33(3):981-92.
8
Electrophysiological study of neuromuscular blocking action of cobra neurotoxin.眼镜蛇神经毒素神经肌肉阻滞作用的电生理研究
Br J Pharmacol Chemother. 1966 Nov;28(2):172-81. doi: 10.1111/j.1476-5381.1966.tb01883.x.
9
Action of crotoxin and crotactin from the venom of Crotalus durissus terrificus (South American rattlesnake) on the frog neuromuscular junction.来自南美响尾蛇（Crotalus durissus terrificus）毒液中的响尾蛇毒素和响尾蛇肌动蛋白对青蛙神经肌肉接头的作用。
J Physiol. 1971 Jan;212(2):34P-35P.
10
Biological roles of the two components of crotoxin.响尾蛇毒素两种成分的生物学作用。
Proc Natl Acad Sci U S A. 1971 Jul;68(7):1560-3. doi: 10.1073/pnas.68.7.1560.