Kumita S, Nishimura T, Uehara T, Shimonagata T, Hayashida K, Katafuchi T
Department of Radiology, National Cardiovascular Center, Osaka.
Kaku Igaku. 1993 Jun;30(6):621-6.
On exercise 201Tl scintigraphy in coronary artery disease, left ventricular transient dilatation (LVTD) and increased lung uptake were noted as a marker of multivessel critical stenosis. To compare the two markers of 99mTc-methoxyisobutyl isonitrile (MIBI) and 201Tl, planar and SPECT myocardial scintigraphy were performed with both radiopharmaceuticals in 27 patients with ischemic heart disease. Lung uptake (lung/max myocardial ratio) of MIBI was significantly lower than that of 201Tl, but the relationship of the lung uptake was linearly correlated (r = 0.77). The LVTD ratio (mean radial ratio = m-RR) was determined by the mean radius of the immediate postexercise short axial image by that of rest (redistribution) image. There was no significant correlation between the m-RR of 201Tl and that of MIBI (r = 0.27). We suggest that the mechanism of LVTD is due to not only subendmyocardial ischemia but also another factors.
在冠心病患者的运动铊-201心肌显像中，左心室短暂扩张（LVTD）和肺摄取增加被视为多支冠状动脉严重狭窄的标志。为比较锝-99m甲氧基异丁基异腈（MIBI）和铊-201这两种标志物，对27例缺血性心脏病患者分别使用这两种放射性药物进行了平面及单光子发射计算机断层扫描（SPECT）心肌显像。MIBI的肺摄取（肺/最大心肌比值）显著低于铊-201，但肺摄取之间的关系呈线性相关（r = 0.77）。LVTD比值（平均径向比值=m-RR）通过运动后即刻短轴图像的平均半径与静息（再分布）图像的平均半径之比来确定。铊-201的m-RR与MIBI的m-RR之间无显著相关性（r = 0.27）。我们认为LVTD的机制不仅是由于心内膜下缺血，还与其他因素有关。
