Paton S, Wiss K, Lyon N, Baden L, Gellis S E
Dermatology Program, Children's Hospital, Boston, Massachusetts.
Pediatr Dermatol. 1993 Jun;10(2):177-81. doi: 10.1111/j.1525-1470.1993.tb00050.x.
A 4-month-old boy had a faint, confluent, macular erythema involving the forehead, nose, and philtrum, and matlike telangiectases over the forehead and eyelids. The clinical features, course, and laboratory studies were characteristic of neonatal lupus erythematosus. He was otherwise healthy and the product of a preterm twin pregnancy complicated by the development of maternal HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome. The patient had elevated Ro(SSA) and La(SSB) antibody titers, and studies performed on maternal blood disclosed positive antinuclear antibodies and elevated Ro and La antibody titers.
一名4个月大的男婴前额、鼻部和人中处有淡红色、融合性斑疹,前额和眼睑有席状毛细血管扩张。临床特征、病程及实验室检查符合新生儿红斑狼疮。患儿其他方面健康,系早产双胎妊娠产物,母亲孕期并发HELLP(溶血、肝酶升高、血小板减少)综合征。患儿Ro(SSA)和La(SSB)抗体滴度升高,对母亲血液检测发现抗核抗体阳性及Ro和La抗体滴度升高。