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[新生儿红斑狼疮与母体HELLP综合征:存在发病机制上的联系吗?]

[Neonatal lupus erythematosus and maternal HELLP syndrome: is there a pathogenetic link?].

作者信息

Freyschmidt-Paul P, Rieger C H, Happle R, Hoffmann R

机构信息

Hautklinik der Philipps-Universität Marburg.

出版信息

Hautarzt. 1998 Aug;49(8):662-5. doi: 10.1007/s001050050806.

Abstract

A newborn boy developed annular erythematous lesions on his entire body. Histopathological examination showed typical features of lupus erythematosus. His mother was positive for anti-Ro/SSa and anti-La/SSb antibodies. Neonatal lupus erythematosus was diagnosed. During pregnancy the mother had suffered from HELLP syndrome. The reported case points out the necessity to differentiate HELLP syndrome from first manifestation of lupus erythematosus during pregnancy. A direct causal relationship between neonatal lupus erythematosus and HELLP syndrome of the mother seems to be unlikely.

摘要

一名男婴全身出现环形红斑性皮损。组织病理学检查显示为红斑狼疮的典型特征。其母亲抗Ro/SSa和抗La/SSb抗体呈阳性。诊断为新生儿红斑狼疮。母亲在孕期曾患HELLP综合征。该报道病例指出,孕期有必要将HELLP综合征与红斑狼疮的首发表现相鉴别。新生儿红斑狼疮与母亲的HELLP综合征之间似乎不太可能存在直接因果关系。

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