Moritz A, Grünbaum E G
Medizinischen und Gerichtlichen Veterinärklinik I, Lehrstuhl für Innere Krankheiten der Kleintiere, Justus-Liebig-Universität Giessen.
Tierarztl Prax. 1993 Jun;21(3):243-51.
In the differential diagnosis of neoplastic diseases of blood cells or their precursors, cytological examination of bone marrow is a valuable diagnostic tool. Depending on the expected cell type, an aspiration followed by clinical-cytological examination, or a biopsy followed by histopathological examination is indicated. In all unclear cases of cytopenia, if blood parasites or a lymphatic leukemia without tumors are suspected or in myeloproliferative diseases, bone marrow cytology can provide the diagnosis. If the aspiration of bone marrow is not possible in spite of correct technique (punctiosicca), myelofibrosis must be suspected. The diagnosis is confirmed by bone marrow biopsy. In the most common form of leukemia in dogs, the lymphosarcomatosis, a bone marrow biopsy can be helpful in assessment of the prognosis.
在血细胞或其前体细胞的肿瘤性疾病的鉴别诊断中，骨髓细胞学检查是一种有价值的诊断工具。根据预期的细胞类型，可进行穿刺后进行临床细胞学检查，或进行活检后进行组织病理学检查。在所有不明原因的血细胞减少病例中，如果怀疑有血液寄生虫或无肿瘤的淋巴细胞白血病，或在骨髓增殖性疾病中，骨髓细胞学检查可提供诊断。如果尽管技术正确（干抽）仍无法进行骨髓穿刺，则必须怀疑骨髓纤维化。通过骨髓活检可确诊。在犬类最常见的白血病形式——淋巴肉瘤病中，骨髓活检有助于评估预后。
