温和型大肠杆菌噬菌体186建立和维持溶原状态的基因。
Genes for the establishment and maintenance of lysogeny by the temperate coliphage 186.
作者信息
Lamont I, Richardson H, Carter D R, Egan J B
机构信息
Department of Biochemistry, University of Adelaide, Australia.
出版信息
J Bacteriol. 1993 Aug;175(16):5286-8. doi: 10.1128/jb.175.16.5286-5288.1993.
Abstract
To identify the genes in coliphage 186 that are required for lysogeny, we isolated clear-plaque mutants. Complementation studies and DNA sequencing identified two genes, the cI gene for the immunity maintenance repressor and the cII gene, which is required only for the establishment of lysogeny. One mutant carried a change in the LexA-binding site controlling expression of the antirepression protein Tum.
摘要
为了鉴定噬菌体186中溶原性所需的基因，我们分离了清亮噬菌斑突变体。互补研究和DNA测序鉴定出两个基因，即用于维持免疫的阻遏物的cI基因和仅在溶原性建立时才需要的cII基因。一个突变体在控制抗阻遏蛋白Tum表达的LexA结合位点发生了变化。
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