Lehrer P M, Hochron S M, Isenberg S, Rausch L, Carr R
Department of Psychiatry, Robert Wood Johnson Medical School, Piscataway, NJ 08854.
J Psychosom Res. 1993 Jul;37(5):515-21. doi: 10.1016/0022-3999(93)90007-3.
The Asthma Symptom Profile (ASP) assesses phasic changes in three dimensions of asthma symptoms: intensity, unpleasantness, and quality of sensations. Quantification data on verbal descriptors were gathered from 46 adult asthmatics for each of these scales, using bimodality scaling: i.e., with numerical estimates and drawing lines varying length. Close agreement was obtained between these two modalities. The ASP was analyzed before and after a bronchodilator in 44 asthmatics using ipratropium bromide (IB). Forty of these subjects were also tested in a placebo condition. Although ASP changes produced by IB were no greater than those produced by the placebo, correlations with changes in spirometry variables were significant. There were no significant differences in correlations with line drawings vs. numerical ratings. The ASP appears to be useful measure of phasic changes in asthma symptoms. Asthmatics with mild airway obstruction do not appear to be able to discriminate small changes in airway function.
哮喘症状概况（ASP）评估哮喘症状三个维度的阶段性变化：强度、不适感和感觉性质。使用双峰标度法，即通过数值估计和绘制不同长度的线条，从46名成年哮喘患者中收集了关于这些量表中每个量表的言语描述符的量化数据。这两种方式之间获得了高度一致性。在44名使用异丙托溴铵（IB）的哮喘患者中，在使用支气管扩张剂前后对ASP进行了分析。其中40名受试者也在安慰剂条件下进行了测试。尽管IB产生的ASP变化不大于安慰剂产生的变化，但与肺功能测定变量变化的相关性是显著的。在线条图与数值评分的相关性方面没有显著差异。ASP似乎是哮喘症状阶段性变化的有用指标。轻度气道阻塞的哮喘患者似乎无法辨别气道功能的微小变化。
