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急性大鼠模型中微创近端胃迷走神经切断术

Proximal gastric vagotomy by minimally invasive methods in an acute rat model.

作者信息

Wittgen C M, Schneider T A, Fitzgerald S D, Panneton W M, LaRegina M C, Johnson S, Kaminski D L, Andrus C H

机构信息

Department of Surgery, St. Louis University School of Medicine, St. Louis University Hospital, MO 63110-0250.

出版信息

Surg Endosc. 1993 Jul-Aug;7(4):319-24. doi: 10.1007/BF00725949.

DOI:10.1007/BF00725949
PMID:8351605
Abstract

In this prospective study, minimally invasive methods of proximal gastric vagotomy (PGV) were investigated in male Sprague-Dawley rats. Completeness of vagotomy by traditional operative therapy, by laser denervation of the gastric serosa, and by subserosal or transmucosal injections of chemoneurolytic agents was evaluated with postoperative Congo red testing, ulcerogenic stimulation of the gastric mucosa, and histochemical labeling of whatever vagal fibers remained in the gastric wall. Short-term results demonstrate that successful PGV can be performed with minimally invasive methods.

摘要

在这项前瞻性研究中,对雄性斯普拉格-道利大鼠的近端胃迷走神经切断术(PGV)的微创方法进行了研究。通过术后刚果红试验、胃黏膜致溃疡刺激以及对胃壁中残留的任何迷走神经纤维进行组织化学标记,评估了传统手术治疗、胃浆膜激光去神经支配以及浆膜下或经黏膜注射化学神经溶解剂进行迷走神经切断术的完整性。短期结果表明,PGV可以通过微创方法成功实施。

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1
Proximal gastric vagotomy by minimally invasive methods in an acute rat model.急性大鼠模型中微创近端胃迷走神经切断术
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Serum group I pepsinogens after consecutive stimulations with insulin and pentagastrin in unoperated duodenal ulcer patients and in duodenal ulcer patients after proximal gastric vagotomy.未手术的十二指肠溃疡患者以及近端胃迷走神经切断术后的十二指肠溃疡患者在接受胰岛素和五肽胃泌素连续刺激后的血清I组胃蛋白酶原。
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本文引用的文献

1
Innervation of the gastric wall related to acid secretion: a light and electron microscopy study on rats, rabbits and guinea pigs.与胃酸分泌相关的胃壁神经支配:大鼠、兔和豚鼠的光镜与电镜研究
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Brainstem projections of sensory and motor components of the vagus nerve in the rat.大鼠迷走神经感觉和运动成分的脑干投射
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3
Parietal cell vagotomy: experience with 114 patients with prepyloric or duodenal ulcer.壁细胞迷走神经切断术:114例幽门前或十二指肠溃疡患者的经验
World J Surg. 1982 Sep;6(5):596-602. doi: 10.1007/BF01657874.
4
Anatomical considerations for surgery of the rat abdominal vagus: distribution, paraganglia and regeneration.大鼠腹部迷走神经手术的解剖学考量:分布、副神经节与再生
J Auton Nerv Syst. 1983 Oct;9(1):79-97. doi: 10.1016/0165-1838(83)90133-9.
5
Fundic vagotomy by waveguide CO2 laser: experimental study of a new technique in dogs.经波导二氧化碳激光行胃底迷走神经切断术:犬的一项新技术的实验研究
Lasers Surg Med. 1984;4(4):345-51. doi: 10.1002/lsm.1900040407.
6
Evaluation of topical phenol as a means of producing autonomic denervation of the liver.评估局部应用苯酚作为实现肝脏自主神经去支配的一种方法。
Can J Physiol Pharmacol. 1984 Jul;62(7):849-53. doi: 10.1139/y84-140.
7
Highly selective vagotomy in duodenal ulceration and its complications. A 12-year review.十二指肠溃疡及其并发症的高选择性迷走神经切断术。一项为期12年的回顾。
Ann Surg. 1984 Aug;200(2):181-4. doi: 10.1097/00000658-198408000-00011.
8
Anterior lesser curve seromyotomy and posterior truncal vagotomy in the treatment of chronic duodenal ulcer.前小弯浆膜肌层切开术和后干迷走神经切断术治疗慢性十二指肠溃疡。
Lancet. 1982 Oct 16;2(8303):846-9. doi: 10.1016/s0140-6736(82)90811-x.
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Injection of 5 percent phenol into submucosa of denervated gastric pouch.将5%的苯酚注射到去神经支配胃囊的黏膜下层。
Arch Surg. 1967 Jun;94(6):841-4. doi: 10.1001/archsurg.1967.01330120095017.
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Intrathecal phenol for cancer pain.鞘内注射苯酚治疗癌痛。
Acta Anaesthesiol Scand. 1972;16(1):17-21. doi: 10.1111/j.1399-6576.1972.tb00562.x.