Graves V B, Strother C M, Rappe A H
Department of Radiology, University of Wisconsin Clinical Science Center, Madison 53792-0001.
AJNR Am J Neuroradiol. 1993 Jul-Aug;14(4):787-93.
To evaluate and compare the deliverability, positioning, stability, and effectiveness of aneurysm occlusion and the incidence of parent-artery thrombosis of two different types of platinum coils, using a canine carotid aneurysm model.
29 experimental canine carotid aneurysms (19 lateral, 6 bifurcation, and 4 terminal) were constructed and treated with complex-shaped fibered platinum coils and simple curved nonfibered platinum Guglielmi detachable coils (GDCs).
Fibered complex coils were stable, producing 38% complete aneurysm occlusion and 61% average reduction in aneurysm lumen size but resulting in 19% parent artery occlusions. GDC coils were stable, producing 31% complete aneurysm occlusion and 95% average reduction in aneurysm lumen size with no parent-artery occlusions.
GDC coils produced an average reduction in aneurysm lumen size of 95% without any associated parent-artery occlusions. There were no delayed migrations of GDC coils. The ability to remove, reposition, and detach a coil was the most significant feature of the GDC coil.
使用犬颈动脉动脉瘤模型，评估并比较两种不同类型的铂线圈在动脉瘤栓塞中的输送性、定位性、稳定性、有效性以及母动脉血栓形成的发生率。
构建29个实验性犬颈动脉动脉瘤（19个位于外侧，6个位于分叉处，4个位于末端），并用复杂形状的纤维铂线圈和简单弯曲的非纤维铂 Guglielmi 可脱卸线圈（GDC）进行治疗。
纤维复杂线圈稳定性良好，实现了38%的动脉瘤完全闭塞，动脉瘤腔大小平均缩小61%，但导致19%的母动脉闭塞。GDC 线圈稳定性良好，实现了31%的动脉瘤完全闭塞，动脉瘤腔大小平均缩小95%，且无母动脉闭塞情况。
GDC 线圈使动脉瘤腔大小平均缩小95%，且无任何相关的母动脉闭塞。GDC 线圈无延迟移位。能够取出、重新定位和分离线圈是 GDC 线圈最显著的特点。
