Chow W H, McLaughlin J K, Zheng W, Blot W J, Gao Y T
Division of Cancer Etiology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.
Am J Ind Med. 1993 Jul;24(1):93-100. doi: 10.1002/ajim.4700240109.
Using occupational data for over 3,400 primary liver cancer cases diagnosed between 1980 and 1984 reported to the Shanghai Cancer Registry, and employment information from the 1982 census for the Shanghai population, standardized incidence ratios were computed to generate leads to occupational risks of liver cancer. Among men, a statistically significant excess number of cases was observed for chemical processors, textile workers, wood workers, blacksmiths and machine-tool operators, and material handlers and dock workers. Increased incidence of liver cancer also was observed among female transport equipment operators. These findings indicate that a number of similar occupations are associated with increased risk of primary liver cancer in western countries and China. Although causal inferences cannot be drawn from these data, our study adds to the limited evidence of the potential role of occupational exposures in liver carcinogenesis.
利用上报给上海癌症登记处的1980年至1984年间确诊的3400多例原发性肝癌病例的职业数据，以及1982年上海人口普查的就业信息，计算标准化发病率比以得出肝癌职业风险线索。在男性中，化学加工工人、纺织工人、木工、铁匠和机床操作员以及物料搬运工和码头工人的病例数在统计学上显著过多。女性运输设备操作员中也观察到肝癌发病率增加。这些发现表明，在西方国家和中国，一些类似职业与原发性肝癌风险增加有关。虽然不能从这些数据中得出因果推断，但我们的研究增加了职业暴露在肝癌发生中潜在作用的有限证据。
