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朗格汉斯细胞和其他树突状细胞在病毒性疾病中的作用。

Role of Langerhans cells and other dendritic cells in viral diseases.

作者信息

Sprecher E, Becker Y

机构信息

Department of Molecular Virology, Faculty of Medicine, Hebrew University, Jerusalem, Israel.

出版信息

Arch Virol. 1993;132(1-2):1-28. doi: 10.1007/BF01309840.

DOI:10.1007/BF01309840
PMID:8352653
Abstract

Langerhans cells are part of a vast system of potent antigen-presenting cells known under the name of dendritic cells. During the last decade, much has been learned on dendritic cell involvement in the immune response to infectious diseases. This review briefly summarizes our current understanding of the role played by Langerhans cells and other dendritic cells in the pathogenesis of DNA and RNA virus infections. These data may form the basis for the development of innovative approaches in the diagnosis, prevention, and treatment of viral diseases.

摘要

朗格汉斯细胞是庞大的强效抗原呈递细胞系统的一部分,该系统以树突状细胞之名为人所知。在过去十年中,我们对树突状细胞参与传染病免疫反应的情况有了很多了解。这篇综述简要总结了我们目前对朗格汉斯细胞和其他树突状细胞在DNA和RNA病毒感染发病机制中所起作用的理解。这些数据可能为开发诊断、预防和治疗病毒性疾病的创新方法奠定基础。

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本文引用的文献

1
Role of Langerhans cells and other dendritic cells in disease states.朗格汉斯细胞及其他树突状细胞在疾病状态中的作用。
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Role of T-lymphocyte subsets in recovery from herpes simplex virus infection.T淋巴细胞亚群在单纯疱疹病毒感染恢复中的作用。
单纯疱疹病毒1型经嗅神经途径感染大脑以及病毒潜伏和再激活可能导致儿童和成人出现学习和行为缺陷以及暴力行为:一种观点。
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An analysis of the role of skin Langerhans cells (LC) in the cytoplasmic processing of HIV-1 peptides after "peplotion" transepidermal transfer and HLA class I presentation to CD8+ CTLs--an approach to immunization of humans.“包膜化”经表皮转移后皮肤朗格汉斯细胞(LC)在HIV-1肽胞质加工及HLA I类分子向CD8+ 细胞毒性T淋巴细胞呈递中的作用分析——一种人类免疫方法
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Foot and mouth disease virus replication in bovine skin Langerhans cells under in vitro conditions detected by RT-PCR.通过逆转录聚合酶链反应(RT-PCR)检测体外条件下口蹄疫病毒在牛皮肤朗格汉斯细胞中的复制情况。
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Reduced Langerhans' cell Ia antigen and ATPase activity in patients with the acquired immunodeficiency syndrome.获得性免疫缺陷综合征患者朗格汉斯细胞Ia抗原及ATP酶活性降低。
N Engl J Med. 1984 May 17;310(20):1279-82. doi: 10.1056/NEJM198405173102002.
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Studies on human epidermal Langerhans' cells: II. Activation of human T lymphocytes to herpes simplex virus.
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