Seppelt U, Hantschmann N
Z Gastroenterol. 1977 Jan;15(1):21-8.
Twelve patients (8 males and 4 females) with toxic dilatation of the colon in acute ulcerative colitis were reviewed, who required surgery between 1962 and 1974 at the Department of Surgery, University Kiel. This complication always occured during a relapsing exacerbation of known colitis. Nine patients died. This high operative mortality (75%) was related to faecel sepsis because of praeoperative perforations, operative disruptions of walled-off perforations and to a delaying conservative approach of more than ten days. These results with the onestage coloproctectomy or colectomy with later excision of the rectum urge an early surgical intervention before perforation took place. The diverting ileostomy and decompression colostomy may additionally lead to a better prognosis.
对12例急性溃疡性结肠炎合并结肠中毒性扩张的患者（8例男性，4例女性）进行了回顾性研究，这些患者于1962年至1974年期间在基尔大学外科接受了手术。这种并发症总是发生在已知结肠炎的复发加重期。9例患者死亡。这种高手术死亡率（75%）与术前穿孔导致的粪便败血症、手术中封闭穿孔的破裂以及超过十天的延迟保守治疗方法有关。一期结肠直肠切除术或结肠切除术加后期直肠切除的这些结果促使在穿孔发生前尽早进行手术干预。转流性回肠造口术和减压性结肠造口术可能会带来更好的预后。
