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[致病微生物与吸附剂聚甲基硅氧烷的相互作用]

[The interaction of pathogenic microorganisms with the sorbent polymethylsiloxane].

作者信息

Dikova I G, Il'chenko O I, Ruban V I, Samodumova I M, Sidel'nikova L F

出版信息

Mikrobiol Zh (1978). 1993 May-Jun;55(3):47-53.

PMID:8355629
Abstract

The method of electron microscopy has been used to study adhesion of the microbic cells of standard strains of Staphylococcus aureus, Escherichia coli and fungi of genus Candida on the organosilicon sorbent polymethylsiloxane (PMS) and medicamentous complex containing it. This complex contains furazolidone and metronidazole immobilized on silver ions-modified PMS. It is shown that the adhesion of microorganisms is accompanied by their destruction whose rate on pure PMS and medicamentous complex is different. Using experimental data the assumptions are advanced concerning the mechanism of the PMS interaction with Gram-positive and Gram-negative microorganisms as well as with fungi of genus Candida.

摘要

运用电子显微镜方法研究了金黄色葡萄球菌、大肠杆菌标准菌株的微生物细胞以及念珠菌属真菌在有机硅吸附剂聚甲基硅氧烷(PMS)及其含有的药物复合物上的黏附情况。该复合物含有固定在银离子改性PMS上的呋喃唑酮和甲硝唑。结果表明,微生物的黏附伴随着它们的破坏,其在纯PMS和药物复合物上的破坏速率不同。利用实验数据,提出了关于PMS与革兰氏阳性菌、革兰氏阴性菌以及念珠菌属真菌相互作用机制的假设。

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