Pereverzev N A, Salov V F, Grigorian G Iu, Popov V L
Zh Mikrobiol Epidemiol Immunobiol. 1994 Jan-Feb(2):3-7.
The electron-microscopic study of the mechanism of interaction between liposomes of different sizes and gram-positive and gram-negative microorganisms has been made. As shown in this study, gram-positive microorganisms do not come into direct contact with liposomes. gram-negative microorganisms actively contact with small-size (100-200 nm) and medium-size (200-300 nm) liposomes. Large-size liposomes (greater than bacterial cells) "ingest" microorganisms themselves, thus facilitating the development of destructive changes in them.
已对不同大小的脂质体与革兰氏阳性和革兰氏阴性微生物之间相互作用的机制进行了电子显微镜研究。如本研究所示,革兰氏阳性微生物不与脂质体直接接触。革兰氏阴性微生物会主动与小尺寸(100 - 200纳米)和中等尺寸(200 - 300纳米)的脂质体接触。大尺寸脂质体(大于细菌细胞)会“吞噬”微生物本身,从而促使微生物发生破坏性变化。