[Studies of the mechanism of bacterial inactivation after administration of the preparation Polchlor K].

The purpose of the study was to determine the effect of chloroiodic complex compound with non-ionic surface active substances such as Polchlor K on the kinetics of dying, activity of bacterial dehydrogenases and glucosidases as well as ultrastructure of bacterial cells on the example of Escherichia coli and Staphylococcus aureus. The evaluation of the kinetics of bacteria dying under the preparation activity revealed higher activity against E. coli than S. aureus. It was found that the preparation in bactericidal concentrations decreased significantly dehydrogenase activity in the examined microorganisms and also affects the changes in their ultrastructure. The cell dying was mainly due to structure-functional lesions in the cytoplasmic membrane--initially inactivation of respiratory enzymes localized inside the cytoplasmic membrane and furthermore its structural lesion.