Mal'ceva N I, Zhimulev I F
Laboratory of Molecular Cytogenetics, Siberian Division Russian Academy of Sciences, Novosibirsk.
Mol Gen Genet. 1993 Aug;240(2):273-6. doi: 10.1007/BF00277066.
In the polytene nuclei of germ-line cells (ovarian pseudonurse cells) of Drosophila melanogaster females mutant for otu11 (ovarian tumor), the pericentric heterochromatin is much more abundant than in somatic salivary gland cells. This is due to the degree of heterochromatin compaction (and consequently the level of underreplication) being lower in the nurse cells than in the salivary gland cells. The lower level of compaction probably results in a very low degree of position effect gene inactivation in the ovarian nurse cells.
在黑腹果蝇雌性otu11(卵巢肿瘤)突变体的生殖系细胞(卵巢假滋养细胞)的多线核中,着丝粒周围异染色质比体细胞唾液腺细胞中丰富得多。这是由于滋养细胞中异染色质的压缩程度(以及因此的复制不足水平)低于唾液腺细胞。较低的压缩水平可能导致卵巢滋养细胞中位置效应基因失活的程度非常低。