鉴定一种RNA病毒的结构糖蛋白为核糖核酸酶。
Identification of a structural glycoprotein of an RNA virus as a ribonuclease.
作者信息
Schneider R, Unger G, Stark R, Schneider-Scherzer E, Thiel H J
机构信息
Department of Biochemistry, Faculty of Natural Sciences, University of Innsbruck, Austria.
出版信息
Science. 1993 Aug 27;261(5125):1169-71. doi: 10.1126/science.8356450.
One of the three structural glycoproteins of classical swine fever virus (CSFV) is E0, a disulfide-bonded homodimer that induces virus-neutralizing antibodies and occurs in a virion-bound as well as a secreted form. E0 was shown to be similar to a family of fungal and plant ribonucleases. Purified E0 from CSFV-infected cells was a potent ribonuclease specific for uridine and inhibitable by zinc ions.
经典猪瘟病毒（CSFV）的三种结构糖蛋白之一是E0，它是一种通过二硫键结合的同型二聚体，可诱导病毒中和抗体，以病毒体结合形式以及分泌形式存在。E0被证明与真菌和植物核糖核酸酶家族相似。从感染CSFV的细胞中纯化得到的E0是一种对尿苷具有特异性、可被锌离子抑制的强效核糖核酸酶。
Zotero 插件