Yamazaki H, Inoue T, Ikeda H, Tang J T, Murayama S, Teshima T, Otani M, Kozuka T
Department of Radiation Oncology, Osaka University Medical School, Japan.
Strahlenther Onkol. 1993 Aug;169(8):481-5.
Between December 1991 and August 1992, five patients with recurrent cancer in the pelvic area (four gynecological cancers and one rectal cancer) were treated at Osaka University Hospital with a remote afterloading interstitial implantation employing the template technique. External irradiation (40 to 50 Gy) was performed in four cases one to four weeks before brachytherapy. Interstitial high-dose-rate brachytherapy (24 to 40 Gy/four to eight fractions/two to four days) was performed twice a day. Three of the five patients achieved complete local tumor control. The remaining two patients obtained symptom relief. There were no complications serious enough to need surgical treatment. Moreover, this procedure is well tolerated and therefore an effective modality for elderly and frail patients.
1991年12月至1992年8月期间，大阪大学医院对5例盆腔复发性癌症患者（4例妇科癌症和1例直肠癌）采用模板技术进行了远程后装组织间植入治疗。4例患者在近距离放疗前1至4周接受了外照射（40至50 Gy）。组织间高剂量率近距离放疗（24至40 Gy/4至8次分割/2至4天）每天进行2次。5例患者中有3例实现了局部肿瘤完全控制。其余2例患者症状得到缓解。没有严重到需要手术治疗的并发症。此外，该治疗方法耐受性良好，因此对于老年和体弱患者是一种有效的治疗方式。
