1990年至1992年献血者中的HIV血清阳性率：患病率、输血相关感染残余风险估计及流行病学

[HIV seropositivity in blood donors from 1990 to 1992: prevalence, estimation of residual risk of transfusion-related infections and epidemiology].

作者信息

Couroucé A M

机构信息

Institut National de Transfusion Sanguine, Paris.

出版信息

Rev Fr Transfus Hemobiol. 1993 Jul;36(4):327-37. doi: 10.1016/s1140-4639(05)80238-2.

DOI:10.1016/s1140-4639(05)80238-2

PMID:8357445

Abstract

In France, HIV seroprevalence in blood donations still decreased from 1990 to 1992 with an important diminution in 1992, in first time donors as well as in regular donors. During the last 1992 semester, this prevalence reached 0.051%: 0.19% and 0.026% in donations from first time and regular donors respectively. The residual risk was estimated to be 1 for 580,000 donations in 1992 (CI 95% = 1/2,000,000 to 1/330,000). Sex ratio was 3.7 and 3.4 in 1990 and 1991 and increased to 5.5 in 1992 due to a very small number of seropositive women, which seems to be an important epidemiological indicator. The major at-risk group is still represented by homo-bisexual men.

摘要

在法国，1990年至1992年期间，献血者中的艾滋病毒血清阳性率持续下降，1992年出现大幅下降，首次献血者和定期献血者均是如此。在1992年的最后一个学期，这一患病率达到0.051%：首次献血者的献血中该患病率为0.19%，定期献血者的献血中为0.026%。1992年，估计每580,000次献血的残余风险为1（95%置信区间=1/2,000,000至1/330,000）。1990年和1991年的性别比分别为3.7和3.4，1992年由于血清阳性女性数量极少，性别比增至5.5，这似乎是一个重要的流行病学指标。主要的高危群体仍然是男同性恋者。