Bisset J P, Poirier R, Roux F, Sauvan R, Kleisbauer J P
Pathol Biol (Paris). 1978 Sep;26(6):353-4.
In a series of 52 patients with bronchogenic carcinoma serum levels of beta2-microglobulin (beta2m) and carcino-embryonic antigen (CEA) were studied. No correlation was found between the increase of beta2m (greater than 3,2 mg/l) and CEA (greater than 40 ng/l). High levels were found in 10 % of cases for CEA and in 30% of cases for beta2m. The follow-up of serum levels of beta2m and CEA was studied during the evolution of the disease through monthly assays. Upon 15 cases followed, the same dissociation between beta2m and CEA was observed.
对52例支气管源性癌患者的血清β2微球蛋白(β2m)和癌胚抗原(CEA)水平进行了研究。未发现β2m升高(大于3.2mg/L)与CEA升高(大于40ng/L)之间存在相关性。CEA在10%的病例中水平较高,β2m在30%的病例中水平较高。通过每月检测,在疾病进展过程中对β2m和CEA的血清水平进行了随访。在随访的15例病例中,观察到β2m和CEA之间同样存在分离现象。