Trèves R, Clément A, Desproges-Gotteron R, Olivier J P, Beck C
Nouv Presse Med. 1982 Jan 9;11(1):21-4.
Radioimmunological assays of carcino-embryonic antigen (CEA) and beta 2 microglobulin were carried out in 61 cases of malignant bone disease, including myeloma and metastases from carcinomas of the breast and prostate. CEA assays seemed to be of greater interest in mammary cancer metastases and beta 2 microglobulin assays in prostatic cancer metastases and myeloma. The correlation which appeared between CEA levels of the outcome of breast cancer metastases was of assistance in adjusting treatment. Combining CEA and beta 2 microglobulin assays would enhance their usefulness in current practice.
对61例恶性骨病患者进行了癌胚抗原(CEA)和β2微球蛋白的放射免疫测定,这些患者包括骨髓瘤以及乳腺癌和前列腺癌转移患者。CEA测定似乎对乳腺癌转移更有意义,而β2微球蛋白测定对前列腺癌转移和骨髓瘤更有意义。乳腺癌转移结果的CEA水平之间出现的相关性有助于调整治疗。联合CEA和β2微球蛋白测定将提高它们在当前实践中的有用性。