Increased soluble IL-2 receptor in serum of patients with systemic lupus erythematosus.

作者信息

Sawada S, Hashimoto H, Iijma S, Tokano Y, Matsukawa Y, Takei M, Ishikawa H, Kang H, Tomura K, Mitamura K

机构信息

Department of Internal Medicine, Nerima Hikarigaoka Hospital, Nihon University School of Medicine, Japan.

出版信息

Clin Rheumatol. 1993 Jun;12(2):204-9. doi: 10.1007/BF02231527.

We estimated the concentration of soluble IL-2R (sIL-2R) in the serum of patients with systemic lupus erythematosus (SLE) and examined the relationship between the serum levels of sIL-2R and clinical features or laboratory data. We found that elevated levels of sIL-2R were present in the serum of SLE patients with discoid rash, and sIL-2R concentrations were correlated with the soluble CD4 and soluble CD8 concentrations but not with classical serological marker, anti-DNA antibody or complement titer.