Mesa H A, Lang B, Schumacher M, Vaith P, Peter H H
Department of Rheumatology and Clinical Immunology, University of Freiburg Medical Center, Freiburg, Germany.
Clin Rheumatol. 1993 Jun;12(2):253-6. doi: 10.1007/BF02231537.
We present a case of Sneddon's syndrome with high titers of antiphospholipid antibodies (APLA), in which the leading symptom was an incapacitating memory defect. MRI revealed vasculitic lesions of the central nervous system (CNS). Therefore immunosuppressive therapy was started with steroids and cyclophosphamide pulses. The transient beneficial effects of such a therapy will be discussed.
我们报告一例抗磷脂抗体（APLA）滴度高的斯内登综合征病例，其主要症状是使人丧失能力的记忆缺陷。磁共振成像（MRI）显示中枢神经系统（CNS）存在血管炎性病变。因此，开始使用类固醇和环磷酰胺脉冲进行免疫抑制治疗。将讨论这种治疗的短暂有益效果。
