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意大利的肝移植与供体稀缺:成因及伦理考量

Liver transplantation in Italy and the scarcity of donors: causative factors and ethical considerations.

作者信息

Martin A, Rossaro L

机构信息

Cattedra di Malattie dell'Apparato Digerente, Universita di Padova, Italy.

出版信息

Gastroenterol Jpn. 1993 Jul;28 Suppl 6:34-7; discussion 38-41. doi: 10.1007/BF02994291.

DOI:10.1007/BF02994291
PMID:8359633
Abstract

We analyze the current state of liver transplantation (OLTx) in Italy that in the last few years had reached approximately 150 OLTx per year for a population of 58 millions of inhabitants. The need for OLTx in Italy is high and mainly due to the incidence of post-hepatitis and post-alcoholic liver cirrhosis, which are the prevalent indication for OLTx. On the contrary the availability of donor organs in Italy is very low as compared with other European countries, and as a consequence the gap between need and performed OLTx is widening. The reasons for poor donations are multifactorial among which; lack of organization, insufficient ICU care beds, poor knowledge of health personnel. General attitudes of the society and brain death concepts are also involved as a recent survey has demonstrated. Under certain circumstances the patient who cannot be transplanted on time in Italy is allowed to seek for care abroad under the local government economical assistance. Finally some ethical considerations and the proposal for better education of both population and health care providers are advocated.

摘要

我们分析了意大利肝移植(OLTx)的现状。在过去几年中,意大利每年约有150例肝移植手术,其人口为5800万。意大利对肝移植的需求很高,主要是由于肝炎后和酒精性肝硬化的发病率,这是肝移植的主要适应症。相反,与其他欧洲国家相比,意大利供体器官的可用性非常低,因此需求与实际进行的肝移植之间的差距正在扩大。捐赠不足的原因是多方面的,其中包括组织不力、重症监护病房床位不足、医护人员知识欠缺。正如最近一项调查所示,社会的总体态度和脑死亡概念也有影响。在某些情况下,在意大利无法及时接受移植的患者可在当地政府的经济援助下到国外寻求治疗。最后,我们提倡一些伦理考量以及对公众和医疗服务提供者进行更好教育的建议。

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Liver transplantation in Italy and the scarcity of donors: causative factors and ethical considerations.意大利的肝移植与供体稀缺:成因及伦理考量
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本文引用的文献

1
National Institutes of Health Consensus Development Conference Statement: liver transplantation--June 20-23, 1983.美国国立卫生研究院共识发展会议声明:肝移植——1983年6月20日至23日
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Public attitudes and behavior regarding organ donation.公众对器官捐赠的态度和行为。
JAMA. 1985 Jun 7;253(21):3111-5.
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Liver transplantation (1).肝移植(1)。
N Engl J Med. 1989 Oct 12;321(15):1014-22. doi: 10.1056/NEJM198910123211505.
4
Availability of transplantable organs from brain stem dead donors in intensive care units.重症监护病房中脑干死亡供体可用于移植的器官情况。
BMJ. 1991 Jan 19;302(6769):149-53. doi: 10.1136/bmj.302.6769.149.
5
Factors in the development of a liver transplantation programme: experience of 100 consecutive transplantations in Milan's Niguarda Hospital.肝移植项目发展的影响因素:米兰尼瓜尔达医院连续100例肝移植的经验
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