Starzl T E, Demetris A J, Van Thiel D
Department of Surgery, University of Pittsburgh, PA.
N Engl J Med. 1989 Oct 12;321(15):1014-22. doi: 10.1056/NEJM198910123211505.
Advances in the management of both chronic and acute hepatic disease have been made possible and even mandated by the development of liver transplantation. The clinical use of transplantation has proceeded at a rapid pace since a Consensus Development Conference of the National Institutes of Health concluded in June 1983 that liver transplantation had become a service and not simply an experimental procedure. The liver can be transplanted as an extra (auxiliary) organ at an ectopic site, or in the orthotopic location after the removal of the host liver (Fig. 1). This article will focus primarily on the orthotopic procedure. However, there has been renewed interest in the auxiliary operation, which will be discussed separately.
肝脏移植的发展使得慢性和急性肝病的治疗取得了进展,甚至可以说这种进展是必然的。自1983年6月美国国立卫生研究院的一次共识发展会议得出肝脏移植已成为一种常规医疗服务而非仅仅是实验性手术的结论以来,移植技术在临床上的应用进展迅速。肝脏既可以作为额外的(辅助)器官移植到异位部位,也可以在切除宿主肝脏后移植到原位(图1)。本文将主要聚焦于原位移植手术。然而,人们对辅助性手术重新产生了兴趣,这将另行讨论。