Ehrenreich T
Ann Clin Lab Sci. 1977 Jan-Feb;7(1):6-16.
Exposure to a variety of solvents may result in renal disease. Tubular renal disease with anuria occurring fairly promptly after exposure is most commonly seen. There is evidence that some cases of glomerular disease, such as extra-capillary glomerulonephritis and membranous nephropathy, may be causally related to chronic solvent exposure. Their detection may be impeded by the prolonged latent period between exposure and onset of disease, the non-specificity of the glomerular lesions and the non-availability of a history of exposure.
接触多种溶剂可能会导致肾脏疾病。接触后很快出现无尿的肾小管性肾病最为常见。有证据表明,某些肾小球疾病,如毛细血管外肾小球肾炎和膜性肾病,可能与慢性溶剂接触存在因果关系。由于接触与疾病发作之间的潜伏期较长、肾小球病变的非特异性以及缺乏接触史,这些疾病可能难以被发现。