出生后第5天测定血清促甲状腺激素作为先天性甲状腺功能减退症的筛查方法。
Serum thyrotrophin determination on day 5 of life as screening procedure for congenital hypothyroidism.
作者信息
Delange F, Camus M, Winkler M, Dodion J, Ermans A M
出版信息
Arch Dis Child. 1977 Feb;52(2):89-96. doi: 10.1136/adc.52.2.89.
Abstract
In 327 newborns cord blood thyroxine (T4) was 11.8 +/- 0.4 mug/100 ml (SEM) (151.9 +/- 5.1 nmol/l), and serum thyrotrophin (TSH) 6.7+/-1.0 muU/ml. Variability was marked for both T4 and TSH. Remeasured in the same patients on the fifth day of life, the TSH level was 3.7 +/- 1.0 muU/ml, lower than at birth (P less than 0.001), while scattering of TSH values was much smaller, with 99.4 % of values less than 12 muU/ml...
摘要
在327例新生儿中，脐血甲状腺素（T4）为11.8±0.4μg/100ml（标准误）（151.9±5.1nmol/L），血清促甲状腺素（TSH）为6.7±1.0mU/ml。T4和TSH的变异性均很明显。在同一批患儿出生后第5天重新检测，TSH水平为3.7±1.0mU/ml，低于出生时（P<0.001），而TSH值的离散度小得多，99.4%的值低于12mU/ml……
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