Hatton D V, Leach C S, Nicogossian A E
Arch Environ Health. 1977 Jan-Feb;32(1):33-6. doi: 10.1080/00039896.1977.10667250.
Measurements of urinary hydroxylysine glycosides indicate that considerable collagen degradation occurred during the reentry into the earth's atmosphere of the American astronauts of the Apollo-Soyuz mission. Since the crew accidentally inhaled nitrogen dioxide, a recognized pulmonary irritant, and showed clinical and roentgenographic signs of diffuse chemical pneumonitis, it is likely that collagen degradation occurred in the pulmonary parenchyma.
尿羟赖氨酸糖苷的测量结果表明，在阿波罗 - 联盟号任务的美国宇航员重返地球大气层期间，发生了相当程度的胶原蛋白降解。由于机组人员意外吸入了二氧化氮（一种公认的肺部刺激物），并出现了弥漫性化学性肺炎的临床和X线征象，胶原蛋白降解很可能发生在肺实质中。
