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[自身免疫性疾病中实验室数据的界值水平]

[The boundary levels of laboratory data in autoimmune diseases].

作者信息

Watanabe H, Imafuku Y, Ono S, Honda S, Yoshida H

机构信息

Department of Clinical Laboratory Medicine, Fukushima Medical College.

出版信息

Rinsho Byori. 1993 Jun;41(6):637-41.

PMID:8361029
Abstract

The clinical significance of rheumatoid factor, antinuclear antibody, anti-thyroid antibody, CH50 and serologic tests for syphilis (STS) in boundary levels were investigated. The boundary levels were tentatively determined as: RF 5-20 U/ml, ANA 20-40X, anti-thyroid antibody 100-400X and CH50 25-30 U/ml. In STS, cases with biological false positive reaction were examined. In ninety percent of patients with positive anti-thyroid antibody, thyroid antibody, thyroid diseases were demonstrated. However, various disorders were involved at the boundary levels of rheumatoid factor, antinuclear antibody, CH50 and serologic tests for syphilis. To assess the boundary levels of these serological data, it seems important to observe serial data and other clinical and laboratory findings.

摘要

研究了类风湿因子、抗核抗体、抗甲状腺抗体、总补体活性(CH50)及梅毒血清学试验(STS)临界水平的临床意义。临界水平初步确定为:类风湿因子5 - 20 U/ml、抗核抗体20 - 40X、抗甲状腺抗体100 - 400X以及CH50 25 - 30 U/ml。对于梅毒血清学试验,检查了出现生物学假阳性反应的病例。在90%抗甲状腺抗体阳性的患者中,证实存在甲状腺抗体及甲状腺疾病。然而,在类风湿因子、抗核抗体、CH50及梅毒血清学试验的临界水平涉及多种疾病。为评估这些血清学数据的临界水平,观察系列数据以及其他临床和实验室检查结果似乎很重要。

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