Marais J, Porter M J, Dent H, Shawe A, O'Donoghue B
Otolaryngology Unit, Royal Infirmary, Edinburgh, United Kingdom.
Rhinology. 1993 Jun;31(2):81-3.
The differing effects of halothane and isoflurane on nasal mucosal blood-flow was investigated by means of laser-doppler flowmetry in a total of fourteen patients who received one of these inhalational agents during anaesthesia. A trend towards lower nasal flux was seen in the halothane group but, due to insufficient numbers, significance could not be demonstrated. These changes in flux appeared not to be related to the falls in perfusion pressure which were seen in both groups of patients and were thought to be due to locally vasoactive effects.
通过激光多普勒血流仪，对总共14名在麻醉期间接受这两种吸入剂之一的患者，研究了氟烷和异氟烷对鼻黏膜血流的不同影响。氟烷组的鼻通量有降低的趋势，但由于样本数量不足，未能显示出显著性差异。通量的这些变化似乎与两组患者均出现的灌注压下降无关，灌注压下降被认为是由局部血管活性作用引起的。
