Doherty M L, Windle H, Voorheis H P, Larkin H, Casey M, Clery D, Murray M
Faculty of Veterinary Medicine, University College Dublin, Ballsbridge, Ireland.
Vet Rec. 1993 Jun 26;132(26):653-6. doi: 10.1136/vr.132.26.653.
A four-month-old calf had a clinical history of pyrexia, anaemia, weight loss and behavioural abnormality. Clinical examination revealed evidence of regenerative anaemia and a lymphocytosis which was characterised by a relatively large B cell population. The calf deteriorated clinically while under observation and its prescapular and prefemoral lymph nodes became enlarged. Examination of a blood smear revealed the presence of a large number of circulating Trypanasoma theileri. Serological examination showed the presence of the invariant, stage-specific, trypanosome surface antigen, ISG70 and antibodies against ISG70. ISG70 was first identified in the bloodstream forms of Trypanosoma brucei and has not previously been found in T theileri. Clinical recovery was associated with an increase in packed cell volume, a decrease in the levels of circulating anti-ISG70 antibodies and the complete disappearance of circulating ISG70.
一头四个月大的小牛有发热、贫血、体重减轻和行为异常的临床病史。临床检查发现有再生性贫血和淋巴细胞增多的迹象，其特征是B细胞群体相对较大。小牛在观察期间病情恶化，其肩胛前和股前淋巴结肿大。血液涂片检查发现存在大量循环的泰勒氏锥虫。血清学检查显示存在不变的、阶段特异性的锥虫表面抗原ISG70以及针对ISG70的抗体。ISG70最初是在布氏锥虫的血流形式中鉴定出来的，此前在泰勒氏锥虫中尚未发现。临床恢复与红细胞压积增加、循环抗ISG70抗体水平降低以及循环ISG70完全消失有关。
