Kozhedub R G
Zh Vyssh Nerv Deiat Im I P Pavlova. 1993 May-Jun;43(3):507-13.
By calculating correlation coefficients was revealed the positive linear correlation between the conditioned changes of direct and indirect components of the pyramidal tract response pointing to a correlation between changes of synaptic efficiency and coincident shifts of cellular excitability. Coincidence of the maximal value of this connection with that of cellular excitability dependent on the activation of the lateral hypothalamus points to the role of this subcortical motivational structure in starting intracellular reactions leading to a formation of a common molecular substrate underlying interaction of the membrane and synaptic mechanisms. Precedence of the maximal manifestation of this interaction to the highest increase of synaptic efficiency testifies to the contribution of this process to the manifestation of the basic mechanism of conditioned reflex.
通过计算相关系数发现,锥体束反应的直接和间接成分的条件性变化之间存在正线性相关,这表明突触效率的变化与细胞兴奋性的同步变化之间存在相关性。这种联系的最大值与依赖于外侧下丘脑激活的细胞兴奋性的最大值相一致,这表明该皮质下动机结构在启动细胞内反应中发挥作用,从而导致形成膜和突触机制相互作用的共同分子底物。这种相互作用的最大表现先于突触效率的最高增加,这证明了该过程对条件反射基本机制表现的贡献。